Interference with Tripartite Motif-Containing Protein 26 Expression on Proliferation of Glioma Cells
نویسندگان
چکیده
This research aims to study the effect of interference with tripartite motif-containing protein 26 expression on proliferation intracranial glioma cells. randomly selected 60 cases specimens and brain tissue 10 trauma patients as a normal control group. First, cell culture is performed observe growth status Subsequently, small interfering ribonucleic acid technique was used interfere lines A172 U251 The cells were collected for 26, Western blot fluorescence quantitative polymerase chain reaction verify knockout effect, proliferation, clone formation, transfer, invasion experiments performed. Experimental data showed that among patients, samples positive in 46 all negative. performance compared tissue. difference statistically significant (p<0.01). results show can reduce level pre-B-cell leukemia homeobox through correlation time gradient concentration gradient. Tripartite messenger ring finger 6 downstream target gene without affecting homeobox.
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2022
ISSN: ['0250-474X', '1998-3743']
DOI: https://doi.org/10.36468/pharmaceutical-sciences.spl.562